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‘Indeed, that's about appropriate. I search for a Bodily idea of biological techniques inside of a bottom-up way. I believe you could potentially distinguish three traces of exploration in my team in the meanwhile. The very first worries chromosome composition: how do you get yourself a metre-very long DNA polymer folded and organised in such a microscopic cell? We now have made visualisation methods that let us to check how, for example, SMC proteins loop DNA (video on Youtube) as a way to Make up chromosomes.

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A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola

Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart layout in 2005. (nl)

Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes

We use nanofabricated microfluidic structures to sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which evaluate the basic function of spatial confinement at the molecular and mobile degree. Our jobs contain the following:

Dynamic ParB–DNA interactions initiate and preserve a partition condensate for bacterial chromosome segregation

In 1993, as a young and eager affiliate professor at Delft College of Know-how, I'd at first centered the investigate efforts of my team on measuring the electrical conductance of an individual conducting-polymer molecule. Inside two a long time, we ceesdekker experienced established a device during which an individual wire of the phthalocyaninepolysiloxane polymer was related between two closely spaced steel nanoelectrodes.

At this time, we also understood that it ought to be probable to employ one semiconducting carbon nanotube for making a transistor — and we established out to really make it. We stretched particular person semiconducting nanotubes across metallic electrodes and employed the underlying silicon substrate as a gate electrode, establishing The essential 3-terminal format of the discipline-impact transistor (Fig.

‘The concept that You can find such a point being a beginning, a major bang, is already an interesting signpost to take into consideration that there was a creator. But more typically, and on The idea of pure rationality, I also arrive at a Christian interpretation of fact. An atheistic worldview is often a naturalistic worldview: essentially, there are only atoms and all-natural forces that we are able to measure.

2006, first demonstration of molecular sorting in the lab with a chip applying biomotors; discovery of nanobubbles in stable-point out nanopores; and first estimate of electrokinetic Vitality conversion inside of a nanofluidic channel

One example is, we consider the nucleopore complicated, a gateway amongst the mobile nucleus along with the cytoplasm. This is an extremely complicated technique and as a consequence hard to analyze in a mobile, so we use biomimetics. We reconstruct holes then insert specific aspects in the nucleopore advanced to check transport via it at the single-molecule amount.’

Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent layout in 2005. (nl)