What Does ceesdekker.net Mean?
Midway via his job, Cees Dekker reinvented himself. Immediately after a long time of hardcore physics, he shifted his aim to ‘nanobiology’ on the transform in the millennium. A expression he coined himself, being a make a difference of actuality.But how do morality, the dignity of the human being, my working experience of your indicating of lifetime, comply with from your movement of atoms? A purely naturalistic standpoint fails below; a Christian viewpoint, I do think, is a way more affordable way to interpret these aspects of fact.’
Back again in 1991, Sumio Iijima of your NEC Corporation experienced noted the synthesis of carbon nanotubes. Band framework calculations instructed that these nanotubes could show metallic band conduction. This is able to be a major edge in excess of the conducting polymers we experienced explored, which have been, the truth is, disordered semiconductors featuring basically variable-vary hopping conductivity.
Because 2000, Dekker has shifted the leading focus of his operate to biophysics exactly where he reports the properties of single biomolecules and cells using the instruments of nanotechnology. This change of area was driven by his fascination for that remarkable functioning of biological molecular constructions, together with by the lengthy-phrase viewpoint a large number of appealing discoveries can be expected On this subject.[five] Present-day strains of research in his biophysics group are within the areas of:[6]
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and very first ceesdekker at any time examine from the dynamics DNA supercoils and the invention of supercoil hopping
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes
What distinguishes biology from chemistry is always that these components jointly make up a living technique. The trick of mentioned life, I feel, lies in the interactions, the interplay of those molecules. The large dilemma in regards to the origin of life continues to be unanswered. How did we at any time evolve from easy molecules in the extremely intricate systems we see right now? We do not know. I want to work on These types of big, open issues.’
2011, initially in vitro measurements of transportation across just one biomimetic nuclear pore complicated; improvement of multiplexed magnetic tweezers for kilo-molecule experiments; and settled the mechanism of homology recognition in DNA homologous recombination
2003, shown the 1st biosensors manufactured away from a carbon nanotube; settled the structure and mechanism of DNA mend proteins; and discovery of a fresh method for fabricating good-condition nanopores for DNA translocation
Resolving the step size in condensin-driven DNA loop extrusion identifies ATP binding given that the move-generating process
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division
2006, initially demonstration of molecular sorting within a lab on a chip employing biomotors; discovery of nanobubbles in solid-condition nanopores; and initial estimate of electrokinetic energy conversion within a nanofluidic channel
Developments in nanotechnology during the nineteen nineties made developing electronic devices from single molecules a possibility. Cees Dekker recounts how his team developed a area-temperature transistor determined by one carbon nanotube.
Supercoiling-dependent DNA binding: quantitative modeling and applications to bulk and one-molecule experiments